JimJimJimJim
11-29-2011, 08:32 PM
I have a number of high risk features:
Gleason score 9
Positive cores 7/12 (58%) (6/6 x GS9 one side and 1/6 x GS7 other side)
PSA rise of more than 2 in the year before diagnosis
PSA doubling time of 8 months before treatment
MRI shows probable extra capsular extension at left midgland laterally
MRI shows probable extra capsular extension at left base in midline surrounding seminal vesicles and ejaculatory ducts
J-Pouch (from previous ulcerative colitis) relationship to prostate made operation too difficult, and complicated radiotherapy (narrower margins than normal were used.)
Prostate pulled from normal mid-line by previous surgery
J-Pouch bulge has weakened small bowel walls - perhaps easily damaged, hard to repair
After 8 months ADT and HDR brachy/EBRT, my PSA is undetectable.
Heart is fine (130/80). BMD after one year on oral bisphosphonate was high (143%) so bisphosphonate stopped.
I am 19 months post-radiation. My plan is to keep on ADT (Zometa, Casodex (Cosudex in Australia) and Avodart for at least 2 years post-radiation.
Heart is fine. BMD is high. Exercise. Mediterranean diet. I am not worried by my ADT side-effects.
I know intermittent ADT has been shown to be non-inferior. But given my very high risk, I am inclined to remain on continuous therapy.
What do people think?
Gleason score 9
Positive cores 7/12 (58%) (6/6 x GS9 one side and 1/6 x GS7 other side)
PSA rise of more than 2 in the year before diagnosis
PSA doubling time of 8 months before treatment
MRI shows probable extra capsular extension at left midgland laterally
MRI shows probable extra capsular extension at left base in midline surrounding seminal vesicles and ejaculatory ducts
J-Pouch (from previous ulcerative colitis) relationship to prostate made operation too difficult, and complicated radiotherapy (narrower margins than normal were used.)
Prostate pulled from normal mid-line by previous surgery
J-Pouch bulge has weakened small bowel walls - perhaps easily damaged, hard to repair
After 8 months ADT and HDR brachy/EBRT, my PSA is undetectable.
Heart is fine (130/80). BMD after one year on oral bisphosphonate was high (143%) so bisphosphonate stopped.
I am 19 months post-radiation. My plan is to keep on ADT (Zometa, Casodex (Cosudex in Australia) and Avodart for at least 2 years post-radiation.
Heart is fine. BMD is high. Exercise. Mediterranean diet. I am not worried by my ADT side-effects.
I know intermittent ADT has been shown to be non-inferior. But given my very high risk, I am inclined to remain on continuous therapy.
What do people think?